Do not accept every mission you see; the older ones will be deleted, and you cannot retrieve them once they are gone. This applies equally if you decide to remove them from your list.
Do not complete the away team until the event resets. There is sometimes an Away Team—BP event battle pass.
Only construct a de-sealing rod if you intend to use it. If you create the rod and then decide the vault isn’t worth it, the rod will be removed once the vault closes.
Don’t click on the cloak upgrade until you are at the right level, have the correct ship, and possess a cloaking device. If you do this too soon, you will receive a new daily task that you can’t complete.
Take your time with leveling up. Focus on maximizing everything in the tech tree and buildings first.